the levels at which no health effects occur and. The developing fetus and the juvenile animal did not appear to be more sensitive than the adult animal to the effects of acephate. Both chemicals have a low potential to contaminate groundwater due to their rapid breakdown in the environment and the lack of field evidence to suggest that the use of acephate results in groundwater contamination. The PMRA is requesting feedback on the use pattern for these uses. Changes to label statements, including precautionary statements and buffer zones for nontarget aquatic habitats are required as a result of the environmental risk assessment. Regulatory Directive DIR2001-03, PMRA Re-evaluation Program, presents the details of the re-evaluation activities and program structure. The pellet formulation has since been registered for use on tobacco only. Proposed REIs range from 12 hours to 20 days. The PMRA conducted a risk assessment for acephate in 2004 based on available information at the time and published a proposed re-evaluation decision for public consultation (PACR2004-40). The estimated chronic risk for acephate and methamidophos in food and drinking water was not of concern. What Does Health Canada Consider When Making a Re-evaluation Decision? 630 Freedom Business Center, Suite 402. During the comment period for PACR2004-40, the registrant indicated that a pellet formulation would be an alternative to a closed system for the soluble powder formulation. Acephate is an organophosphate insecticide used to control a broad range of insect pests on a wide variety of sites including forests and woodlots (Christmas tree plantations, farm woodlots, tree nurseries, shelter belts, shade trees), right of ways and municipal parks (excluding national & provincial parks), greenhouse ornamentals, terrestrial food and feed crops (Brussels sprouts, cabbage, cauliflower, celery, field crisphead lettuce, seed and sweet corn, bell pepper, potato, field tomato, cranberry, tobacco, Saskatoon berry) and outdoor ornamentals (numerous flowers, shrubs and trees). “Decision statement” as required by subsection 28(5) of the Pest Control Products Act. $25.99 $ 25. Environmental risks to birds and small wild mammals were identified for all outdoor foliar uses applied by mist blowers or airblast application equipment and were not shown to be acceptable. 610-491-2800 The estimated acute exposure for acephate and methamidophos in food and drinking water was of concern based on initial modelled drinking water concentrations. The proposed regulatory decision pertaining to human health was presented in PRVD2016-01, which included, among other mitigation measures, a prohibition of foliar application in residential areas, the cancellation of uses on potatoes, and the replacement of the soluble powder formulation with a pellet formulation. It is also used to control ants, wasps, cockroaches, earwigs and other insects in and around residences, institutions, and … If you would like to comment, please request the full consultation document. At one time acephate was used commonly in and around homes, but most of those uses are no longer allowed. It also proposes additional risk-reduction measures to further protect human health and the environment. The active ingredient in ACEPHATE 75 SP is acephate, a water soluble insecticide readily absorbed by plant roots and foliage to give systemic control of feeding insects. Therefore, mitigation measures are required in order to reduce potential exposure of nontarget organisms and reduce environmental risks. Proposed protective measures to reduce worker exposure require consultation with user groups to determine their acceptability. No data was available to assess handler exposure from hand-held mist blowers for mist application in greenhouses. This document (PRVD2019-04) is subject to a 90-day public consultation period, during which the public including the pesticide manufacturers and stakeholders may submit written comments and additional information to the PMRA Publications Section. If acephate is used at labelled application rates without any risk reduction measures, it has the potential to cause adverse effects in the organisms listed above. the levels to which people may be exposed. The re-evaluation decision document will include the final re-evaluation decision, the reasons for it and a summary of comments received on the proposed re-evaluation decision with Health Canada’s responses. Other labelled uses of acephate are proposed for continued registration with mitigation measures to protect human health and/or the environment. Under the authority of the Pest Control Products Act , all registered pesticides must be regularly re-evaluated by Health Canada’s Pest Management Regulatory Agency (PMRA) to ensure that they continue to meet current health and environmental safety standards and continue to have value. Acephate is a systemic insecticide with long lasting residual activity (typically 10 to 21 days), which is absorbed and transported throughout the plant, thereby protecting the whole plant. Thus, dietary exposure and risk assessments were conducted for both acephate and methamidophos. To obtain a full copy of Proposed Re-evaluation Decision PRVD2016-01 Acephate please contact our publications office. Specifically, stakeholders are asked to comment on the feasibility of changes to application timing. All products containing acephate registered in Canada are subject to PRVD2019-04. As a result, a risk assessment for the pellet formulation was also conducted for all foliar, soil injection and some tree injection application scenarios currently registered on the label of the soluble powder product. ORTHENE 75% SP (Eng) – PM091806 Page 3 of 12 FIRST AID If swallowed, induce vomiting and obtain medical attention or call a poison control centre IMMEDIATELY. Most uses of acephate have value in the food and non-food agriculture industry and are not of concern to human health or the environment when used according to revised label directions. INSECTICIDE RESISTANCE WARNING For insecticide resistance management, TITAN Acephate 970 SG Insecticide is a Group 1B insecticide. Stakeholder feedback is therefore critical in determining whether these pests are expected to be controlled under the proposed restrictions. MRLs are specified for acephate and methamidophos on a wide range of commodities. The resistant individuals can eventually dominate the insect population if … All comments received during the 90-day public consultation period will be taken into consideration in preparation of a re-evaluation decision document,Footnote 2 which could result in revised risk mitigation measures. If you would like to comment, please request the full consultation document. These methods consider the unique characteristics of sensitive subpopulations in both humans (for example, children) and organisms in the environment (for example, those most sensitive to environmental contaminants). Acephate 97UP can be mixed in the slurry tank with most of the fungi- cide seed treatments in common use. With refined modelled drinking water concentrations and in consideration of mitigation measures and refinements as discussed above, the ARI was greater than 20 for infants and all other population subgroups. There are limited viable alternative active ingredients to acephate available for the control of tarnished plant bug on celery and pepper maggot on peppers. Therefore, risks of concern were not identified with this use. The available studies did not indicate a concern for an effect on the immune system. Dietary risks from food and drinking water are not of concern provided that proposed mitigation measures are implemented. In studies of insecticides commonly used in cotton, acephate was shown to be very toxic to adult Microplitis croceipes parasitoids, and caused 100% mortality at the lowest recommended field rates. The mitigation measures considered included the removal of acephate use on potatoes, the reduction of application rates and number of applications per season, as well as increasing minimum application intervals for several crop uses. No inhalation data was available to assess postapplication worker exposure from hand-held or stationary foggers in greenhouses. The active ingredient in Acephate 90% SP is absorbed by plants via the roots and foliage to provide systemic control of feeding insects. Changes to application timing, including restriction of application before bloom and during bloom for some crops, are required as a result of the pollinator risk assessment. Although there was some indication of damage to genetic material in cell cultures, in vivo studies showed no evidence of genetic damage. By direct application t… The  Food and Drugs Act prohibits the sale of adulterated food, which includes food containing a pesticide residue that exceeds the established maximum residue limit (MRL). The current MRLs for acephate and methamidophos are listed in Section 9.1.1.3 of PRVD2016-01. It also can be applied as a separate treatment using enough water to give adequate coverage of the seed. Uses • Acephate is an organophosphate insecticide currently registered for use on a variety of field, fruit, and vegetable crops (e.g., cotton, tobacco, cranberries, mint); in food handling At the time that the re-evaluation decision is made, the PMRA will publish an Evaluation Report on acephate in the context of this re-evalulation decision (based on the Science Evaluation of Proposed Re-evaluation Decision PRVD2016-01, Acephate). The PMRA will then publish a Re-evaluation Decision on acephate, which will include the decision, the reasons for it, a summary of comments received on the proposed registration decision and the PMRA’s response to these comments. Conditions of registration may include special precautionary measures on the product label to further reduce risk. Since the 2007 interim mitigation measures for acephate, the PMRA has updated the risk assessments considering new data, inclusion of methamidophos in the risk assessments, and the pellet formulation as a potential replacement of the soluble powder formulation. King of Prussia, PA 19406. When using the pellet formulation with the various application equipment, the calculated MOEs meet the target MOE with minimal mitigation, such as baseline PPE for most crops and a respirator for a few specific uses. The current consultation covers only revisions to the proposed re-evaluation decision presented in PRVD2019-04. While formulating these measures, the PMRA considered the measures proposed in PACR2004-40, the comments received on PACR2004-40, as well as the additional data and use information from the registrant. Details on these considerations are noted in Section 3.4.1 of Proposed Re-evaluation Decision PRVD2016-01, Acephate. No data was available to assess handler and postapplication worker exposure from hand-held or stationary foggers in greenhouses. Health or environmental risk is considered acceptable if there is reasonable certainty that no harm to human health, future generations or the environment will result from use of or exposure to the product under its conditions or proposed conditions of registration. Most of the proposed REIs are agronomically feasible; however, REIs for cut flowers, including cut roses (indoors and outdoors) are considered as unfeasible, therefore, these uses are proposed for cancellation. ORTHENE® 97 insecticide's active ingredient, acephate, is readily absorbed by plant roots and foliage to give both contact activity and systemic control of feeding insects in high-value vegetable crops as well as soybean, cotton and tobacco. If in eyes, flush with water.See a physician or contact a poison The combined chronic risk from exposure to both acephate and methamidophos in food and drinking water was also calculated, as these compounds share a common mechanism of toxicity. Similar action was taken in the United States, where all registrations were terminated in 2009. Generally, dietary exposure from food and water is not of concern if it is less than 100% of the acute reference dose or chronic reference dose (acceptable daily intake). To update Toxicological Information on labels: additional information about symptoms and treatment for exposed individuals are required. Reference doses define levels to which an individual can be exposed over a single day (acute) or lifetime (chronic) and expect no adverse health effects. The registration of certain uses of insecticide acephate in Canada is proposed for cancellation. Systemic insecticides have a larger window of application timing than non-systemic insecticides as they are effective for controlling pests even after they have entered the host. Before making a final re-evaluation decision on acephate, the PMRA will consider any comments received from the public in response to Proposed Re-evaluation Decision PRVD2016-01, Acephate. SYSTEMIC INSECTICIDE GROUP 1B INSECTICIDE CAUTION POISON READ LABEL BEFORE USING GUARANTEE: *Acephate.....75% NET CONTENTS: 1.5 kg REGISTRATION NO. As a general use insecticide, it has a residual effect of 10-15 days. Acephate is an organophosphate insecticide. Only uses for which the exposure is well below levels that cause no effects in animal testing are considered acceptable for registration. Please forward all comments to Publications. To obtain a full copy of Proposed Re-evaluation Decision PRVD2019-04, Acephate and Its Associated End-use Products please contact our publications office. Potential exposure to acephate may occur through the diet (for example, food and drinking water), when applying the product, or by entering treated sites. Acephate 97UP is an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. To reduce food and drinking water risk concerns: application rate and maximum number of applications per year are proposed to be reduced, and minimum application intervals are proposed to be increased for certain crops. It is proposed that a label statement prohibiting this specific use in residential areas be added. As a requirement of the continued registration for these uses, new risk-reduction measures are proposed to be included on the labels of certain products. After a re-evaluation of the organophosphate insecticide acephate, Health Canada’s Pest Management Regulatory Agency (PMRA), under the authority of the  Pest Control Products Act, is proposing continued registration of certain products containing acephate for the sale and use in Canada. With implementation of proposed mitigation measures, the risk to the environment is expected to be acceptable when acephate is applied as a foliar spray by ground boom to other sites listed on the label. It was of low acute toxicity via the dermal and inhalation routes of exposure. This proposal affects all end-use products containing acephate registered in Canada. The changes to the MRLs are proposed to account for the phase-out of all methamidophos uses,to reflect the current registered use pattern for acephate, to account for proposed mitigation measures, and to ensure that residues in food do not pose any health risk concerns. Subsequently, the technical registrants of methamidophos voluntarily discontinued all methamidophos products and the registrations expired in 2012. It is used on food crops, citrus trees, as a seed treatment, on golf courses, and in commercial or institutional facilities. Acephate What Additional Scientific Information is Being Requested? The PMRA will accept written comments on Proposed Re-evaluation Decision PRVD2016-01, Acephate up to 60 days from the date of publication of PRVD2016-01. Get contact details & address of companies manufacturing and supplying Acephate, Acetamidophos, 30560-19-1 across India. 630 Freedom Business Center, Suite 402. To protect the environment, the following measures are proposed: Proposed label amendments resulting from these environmental mitigation measures are presented in Appendix II of PRVD2019-04. Acephate is registered for the control of a broad spectrum of insect pests, on a wide range of ornamentals. Acephate was mildly irritating to eyes and skin and was not found to cause an allergic skin reaction. This document (Proposed Re-evaluation Decision PRVD2019-04, Acephate and Its Associated End-use Products) presents revisions to the proposed regulatory decision for the re-evaluation of acephate (PRVD2016-01) with risk mitigation measures to protect the environment along with updates to the environmental evaluation on which the proposed decision was based. 21 May 2019 King of Prussia, PA 19406. You will not receive a reply. Acephate contributes to pest management in the ornamental industry. The final re-evaluation decision will be published taking into consideration the comments and information received. Canada restricts uses of acephate The registration of certain uses of insecticide acephate in Canada is proposed for cancellation. For more information, please refer to the following: Before making a re-evaluation decision on acephate, the PMRA will consider any comments received from the public in response to this consultation document. Residential risks from the foliar use of acephate on trees and ornamentals (trees, shrubs and flowers) are of concern. Acephate is an organophosphate foliar and soil insecticide of moderate persistence with residual systemic activity of about 10–15 days at the recommended use rate. Pesticides and pest management consultations, Consultation on Acephate, Proposed Re-evaluation Decision PRVD2016-01. If the pests cannot be adequately managed under the new application timing, these claims may be removed from the labels. Find here Acephate, Acetamidophos manufacturers, suppliers & exporters in India. Acephate is an insecticide that belongs to the organophosphate group of chemicals.It is typically used as a foliar spray against chewing and sucking insects, such as aphids, leaf miners, Lepidopterous larvae, sawflies, and thrips on fruits, vegetables, potatoes, sugarbeet, vines, rice, hops, ornamentals, and greenhouse crops like peppers and cucumbers. These directions must be followed by law. For tree implant cartridges, exposure and risk were not of concern when used as per label directions, since applicator exposure was minimal. When used according to the revised label directions, acephate does not pose an unacceptable risk to the environment. Consideration of and responses to comments pertaining to the health assessment already received for PRVD2016-01 will be presented in the final re-evaluation decision for acephate. Food containing a pesticide residue that does not exceed the established MRL does not pose an unacceptable health risk. As a result of the re-evaluation of acephate, further risk mitigation measures for product labels are being proposed. While addressing this comment, required changes were made to environmental endpoints used in the assessment. A Proposed Re-evaluation Decision for acephate was first published on 8 January 2016 (PRVD2016-01 ). Target MOEs were achieved only when using extensive mitigation such as full personal protective equipment (PPE), engineering controls, lowered rates or removal of specific uses. Acephate 97up Systemic Insecticide 97% Orthene ( 1 Lb Bag ) Great For Fire Ants" Not For Sale To California. As a result, this causes a build-up … There are no additional data required under section 12 of the Pest Control Products Act. It can also be applied outdoors in residential areas and is often used to control fire ants. Proposed Re-evaluation Decision PRVD2016-01, Acephate is a consultation document that summarizes the science evaluation for acephate and presents the reasons for the proposed re-evaluation decision. Acephate is an organophosphate insecticide used to control a broad range of insect pests on a wide variety of sites including forests and woodlots (Christmas tree plantations, farm woodlots, tree nurseries, shelter belts, shade trees), right of ways and municipal parks (excluding national & provincial parks), greenhouse ornamentals, terrestrial food and feed crops (Brussels sprouts, cabbage, cauliflower, … For enquiries, contact us. Fire Ant Killer Best Value Powder! 610-491-2800 In the absence of data to estimate risk, a label direction specifying “Not for use with fogging equipment” is required. IDENTIFICATION OF THE SUBSTANCE Product Name ACEPHATE 750 SP Insecticide Common Name Acephate Active Ingredient: Acephate (BSI, E-ISO, ANSI, ESA, BPC), (m)(F-ISO, JMAF) Chemical Name: O,S-dimethyl acetylphosphoramidothioate (IUPAC) CAS N o.: 30560-19-1 Registered pesticide product labels include specific directions for use. Pest Management Regulatory Agency 8 January 2016 ISSN: 1925-0967 (PDF version) Catalogue number: H113-27/2016-1E-PDF (PDF version). Once all organophosphate pesticides have been re-evaluated, a cumulative risk assessment will be conducted that will consider potential exposure to all chemicals causing toxicity in the same manner. Limited alternative actives are registered for insect control in potatoes. In laboratory animals, the technical grade active ingredient acephate was slightly or moderately acutely toxic to rats or rabbits via the oral route, but highly toxic to mice. NEW A pellet formulation was determined to be an acceptable alternative to the soluble powder formulation for most uses, which would require registration for the pellet formulation. Health Canada applies internationally accepted risk assessment methods as well as current risk management approaches and policies. Methamidophos, the primary metabolite of acephate, was not fully considered in the acephate risk assessment since a concurrent risk assessment for methamidophos as a registered active ingredient at the time was being conducted. 99 ($2.17/Pound) FREE Shipping. Crops with minor use registrations identified as having particular value are the following: aphids on celery; blackheaded fireworm on cranberry; and the pipette and syringe application method to trees for the control of sucking and chewing insects. When assessing health risks, two key factors are considered: The dose levels used to assess risks are established to protect the most sensitive human population (for example, children and nursing mothers). However, when the proposed mitigation measures such as lowered application rates and revised restricted-entry intervals (REIs) are considered, the risk estimates for postapplication workers are not of concern. Several MRL changes for acephate and methamidophos are proposed as a result of this re-evaluation, as indicated in Section 9.1.1.3 of PRVD2016-01. The Forest industry uses it on pine trees and Christmas trees. Currently, the main product available for foliar applications in various agricultural and horticultural scenarios is packaged as a soluble powder. Acephate contributes to pest management in Canadian food crops. Acephate is applied to golf courses and turf, as well as, to horticulture crops. It should be noted that only information related to the updated environmental risk assessment or its impact on the value of uses will be considered within the context of this consultation. Postapplication occupational risk assessments consider exposure to workers entering treated sites in agriculture and other scenarios. Estimates of exposure did not reach the target margin of exposure (MOE) or aggregate risk index (ARI) for adults and children for all postapplication scenarios and are, therefore, of concern. The combined acute risk could not be determined for acephate and methamidophos due to constraints in comparing the toxicological databases of both compounds. Insecticide. In the absence of data to estimate risk, a label direction specifying “Not for use with fogging equipment” is required. In addition to the site pest combinations listed above, acephate uses identified as grower priorities and registered through the User Requested Minor Use Label Expansion (URMULE) program have value either as the sole active ingredient registered for use on the site to control the listed pest(s), or for resistance management. RESISTANCE WARNING ACEPHATE 750 SP is a group code 1B insecticide. Should you require further information please contact the Pest Management Information Service. With refined modelled drinking water concentrations, the estimated acute exposure ranged from 23-49% of the ARfD for acephate and 33-56% of the ARfD for methamidophos for the various population subgroups. Occupational postapplication risks are not of concern if proposed protective measures are followed. With refined modelled drinking water concentrations, the estimated chronic exposure ranged from 1-3% of the ADI for acephate and 1-2% of the ADI for methamidophos for the various population subgroups. Given that the acute exposure estimates for acephate and methamidophos individually did not exceed 60% of the ARfD at the 99.9th percentile, it is unlikely that the combined risk would be of concern. Active Ingredients: Acephate 98% Acephate is registered to control a broad spectrum of insect pests on a wide variety of crops and contributes to pest management by offering an alternative mode of action for use on Canadian food crops. Occupational (mixer/loader/applicator) risks are not of concern when products are used according to revised label directions and/or products are formulated as a pellet and encapsulated tree implant. Acephate, and its major transformation product methamidophos, enter the environment when acephate is used to control insect pests on a wide variety of sites, including forests and woodlots, terrestrial food and feed crops, and outdoor ornamentals. Based on initial modelled drinking water concentrations, the estimated chronic exposure ranged from 8-36% of the acceptable daily intake (ADI) for acephate and 16-69% of the ADI for methamidophos for the various population subgroups. ACEPHATE 75 SP is an insecticide for control of pests on selected agricultural crops and in certain non-crop areas. Acephate is an organophosphate insecticide used on a variety of crops, including lettuce, celery, peppers, cotton, and beans. Therefore, acute exposure from acephate and methamidophos in food and drinking water are not of concern provided that the mitigation measures outlined in Section 3.4.1 of PRVD2016-01 are implemented. To reach its decisions, the PMRA applies hazard and risk assessment methods as well as policies that are rigorous and modern. Acephate is an insecticide registered to control a broad spectrum of insect pests on a wide variety of crops and use sites, including forest and woodlots, terrestrial food and feed crops, and outdoor ornamentals. Acephate and its major transformation product, methamidophos, break down quickly in soil and water and are not expected to persist in the environment. Application timing of PRVD2016-01 and Christmas trees to golf courses and turf, as indicated in Section 9.1.1.3 of.... To provide systemic control of pests on selected agricultural crops and in certain non-crop.. Using this formulation, target MOEs were not identified with this use % Orthene ( Lb! Is often used to control these pests it can also be applied as result... Was available to assess handler and postapplication worker exposure from hand-held or stationary foggers in greenhouses risk assessments consider to. In PRVD2019-04 labelled uses of acephate, proposed Re-evaluation Decision toxicity in the slurry tank most. 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